U-OK Optimal Health Center

Dr. Elena Koles, MD

alternative medicine chicago

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Medical Testing - Functional and Nutritional Medicine

In addition to regular blood tests offered by physicians, such as CBC, chemical panels, lipid and thyroid tests and so on, Dr. Koles offers unique tests you can't find at a regular doctor's office.

Most tests performed at doctor's offices aim to assess pathology and sickness. They are excellent tools for figuring out if any bodily systems are diseased. With the advent of functional and nutritional medicine, tests have also been developed to identify imbalances and interactions of physiological systems. Rather than wait for disease to strike, integrative physicians can identify and treat a functional imbalance before it becomes a real illness. For chronic conditions, functional laboratory tests can help identify the true cause of disease.

At the U-OK Optimal Health Center, we offer numerous tests that can pinpoint areas of dysfunction in your body. Though we can't list every test we offer, we want to give you a clear idea of testing services available from our office:

Immunology Testing

  • Food Antibody Assessment
  • Inhalants Profile
  • 24 Spice Profile
  • Molds Profile
  • Celiac Profile

Endocrine Testing

  • Comprehensive Thyroid Assessment
  • Bone Resorption Assessment
  • Adrenocortex Stress Profile
  • Comprehensive Melatonin Profile

Metabolic Testing

  • Metabolic Analysis Profile
  • Cellular Energy Profile
  • Comprehensive Detoxification Profile
  • Oxidative Stress Analysis (Blood & Urine)

Gastrointestinal Testing

  • Comprehensive Digestive Stool Analysis
  • Comprehensive Parasitology Panel
  • Vaginosis Profile
  • Intestinal Permeability Assessment
  • Bacterial Overgrowth of the Small Intestine
  • Lactose Intolerance Breath Test
  • H. Pylori Antibody Assay

Nutritional Testing

  • Toxic Element Clearance Profile
  • Elemental Analysis
  • Elemental Analysis, Packed Erythrocytes
  • Toxic Element Exposure Profile
  • Comprehensive Urine Element Profile (24 hr and Creatinine)
  • Amino Acids Analysis
  • Essential & Metabolic Fatty Acids Analysis

BioSET testing


Immunology Testing using both IgG (delayed reaction) and IgE (immediate reaction) antibodies:

Food Antibody Assessment measures serum levels ofIgE and total IgG antibodies for 88 combined or vegetarian foods. The test results are then used to develop a customized rotational diet and supplementation plan.

Inhalants Profile measures serum IgE antibody levels to 36 regional environmental inhalants.

24 Spice Profile measures serum levels ofIgE and total IgG antibodies for 24 frequendy used culinary herbs and spices.

Molds Profile measures serum levels of IgE and total IgE antibodies to 15 common molds

Celiac Profile measures Total IgA to rule out false negatives in IgA immunodeficient individuals, and the Endomysial IgA as a reflex when indicated. Anti-GLiadin IgA and IgG is available to establish levels and use as a monitoring tool for successful elimination of gluten.

Endocrine Testing:

Comprehensive Thyroid Assessment is a comprehensive analysis of thyroid hormone secretion and metabolism, including central thyroid regulation and activity, peripheral thyroid function, and thyroid autoimmunity. This serum test allows Dr. Koles to pinpoint commonly occurring imbalances that underlie a broad spectrum of chronic illness.

Bone Resorption Assessment is a simple, direct urinary assay of pyridinium crosslinks and deoxypyridinoline, useful in identifying current rate of bone loss, lytic bone disease, and efficacy of bone support therapies.

Adrenocortex Stress Profile is a salivary assay of cortisol and DHEA, imbalances of which are associated with ailments ranging from obesity and menstrual disorders to immune deficiency and increased risk of cardiovascular disease. The test also measures insulin.

Comprehensive Melatonin Profile analyzes three saliva samples for the secretion pattern of this important hormone. Melatonin imbalance has been associated with Seasonal Affective Disorder, infertility, sleep disorders, and compromised immune function.

Metabolic Testing:

Metabolic Analysis Profile assesses urine metabolites to evaluate four critical areas of metabolism: gastrointestinal function, cellular energy production, neurotransmitter processing, and amino acid-organic acid balance. Test results can be used to address chronic systemic complaints: fatigue and mood disorders to headaches, muscular/joint pain, and digestive problems.

Cellular Energy Profile evaluates fourteen organic acids that play a pivotal role in the generation of cell energy. Using a urine sample, the test can reveal metabolic distress associated with generalized pain and fatigue, which may arise in response to toxic exposure, nutrient imbalances, digestive dysfunction, and other causes. The profile also analyzes mitochondrial dysfunction and acquired errors of organic acid metals.

Comprehensive Detoxification Profile analyzes saliva, blood, and after- challenge doses of caffeine, aspirin, and acetaminophen in order to assess the Phase I and Phase II functional capacity of the liver to convert and clear toxic substances from the body. This profile includes markers for oxidative stress and important antioxidants. The standard profile analyzes saliva and urine to assess the Phase I and Phase II functional capacity of the liver to convert and clear toxic substances from the body.

Oxidative Stress Analysis (Blood & Urine) identifies markers of hydroxyl radical activity, urine lipid peroxides, reduced glutathione, superoxide dismutase, and glutathione peroxidase, following a challenge dose of aspirin and acetaminophen. Offered by itself or included in the Comprehensive Detoxification Profile. Especially useful in cases of chronic fatigue, xenobiotic exposure, and chronic illnesses.

Gastrointestinal Testing:

Comprehensive Digestive Stool Analysis (CDSA) is a non-invasive test that analyzes digestion and absorption, bacterial balance and metabolism, yeast and immune status. It's indicated for patients with irritable bowel syndrome, indigestion, malabsorption, dysbiosis, other GI-related problems, and many systemic disorders.

Comprehensive Parasitology Panel evaluates stool for presence of parasites and levels of beneficial flora, imbalanced flora, pathogenic bacteria, and yeast. This profile accurately identifies a wide range of protozoal parasites, including amoebae, flagellates, ciliates, coccidia and microsporidia. For patients with abdominal pain, chronic diarrhea, and other GI-related symptoms.

Intestinal Permeability Assessment analyzes urine for the clearance of two non-metabolized sugars, lactulose and mannitol. Identifies "leaky gut" and malabsorption.

Bacterial Overgrowth of the Small Intestine Breath Test measures timed breath samples for hydrogen and methane gases released in response to lactulose challenge. Indicates overgrowth of bacteria in the small intestine, a common cause of Irritable Bowel Syndrom and other chronic symptoms of maldigestion and malabsorption, including bloating, gas, diarrhea, irregularity, and abdominal pain.

Lactose Intolerance Breath Test measures timed breath samples for hydrogen and methane gases released in response to lactose challenge. Detects lactose malabsorption, which often underlies chronic symptoms of bloating, gas, diarrhea, and abdominal pain.

Helicobacter pylori Antibody Assay assays blood for IgG antibodies to H. pylori, the leading cause of peptic ulcers, chronic gastritis, and increased risk of gastric cancer. Also provides a simple and sensitive clinical tool for monitoring eradication therapy.

Nutritional Testing:

Toxicity Testing:

Toxic Element Clearance Profile
(24 hr and Creatinine) measures urinary excretion of 20 toxic metals. This test should be implemented when only a focused evaluation of exposure to toxic metals is desired.

Elemental Analysis examines blood or hair samples for levels of toxic and nutrient elements. Toxicities and nutrient insufficiencies are identified, allowing for targeted interventions.

Elemental Analysis, Packed Erythrocytes measures red blood cell intracellular concentrations of 6 toxic elements and 6 nutrient elements. Indicated for patients suspected of recent toxic element exposure and for evaluation of mineral nutrient status.

Toxic Element Exposure Profile assesses levels of 22 potentially damaging elements using a hair sample. Indicated for patients with suspected exposure to toxic elements.

Comprehensive Urine Element Profile (24 hr and Creatinine) measures urinary excretion of 15 nutrient elements and 20 toxic metals, including "classic" toxics such as lead, mercury, and arsenic, as well as newer technology toxics such as niobium. This is an ideal test for patients suspected of toxic metal exposure as well as potential nutrient mineral wasting.

Amino Acids Analysis examines fasting blood or 24-hour urine samples for 40+ amino acids. Results can provide valuable biochemical information about many disorders, including chronic fatigue, learning disabilities, depression and immune problems.

Essential & Metabolic Fatty Acids Analysis evaluates the level of red cell membrane or plasma fatty acids, imbalances which significantly affect inflammatory and other disorders. By knowing the various fatty acid levels, one can reestablish a balance using nutritional intervention.

BioSET Testing:

BioSET (Bioenergetic Sensitivity and Enzyme Therapy) is a system designed for assessment and elimination of allergies to foods, environmental allergens, chemical sensitivities and many common, and uncommon, allergens. BioSET involves electromagnetic testing with a computerized electro-acupuncture device for acupuncture meridian sensitivity.

Applied Kinesiology, developed by Dr. George Goodheart in 1964, uses bioenergetic feedback through testing the strength of various muscles in the body. This highly individualized, in-depth sytem of analysis, allows the doctor to assess various aspects of a patient's state of health by evaluating and treating postural and muscular imbalances, neurovascular and neurolymphatic points, subluxation, cranial-sacral movement, acupuncture meridians and nutritional status. This is a highly effective treatment system which focuses on whole body care.